While the Saints' defense did not intercept a pass for the first time all season, the unit forced three turnovers on fumbles. The last produced New Orleans' seventh defensive touchdown of the season on Anthony Hargrove's strip, recovery and 1-yard return late in the fourth quarter.
DeAngelo Williams rushed for 149 yards and two TDs, and Carolina gained 182 on the ground. However, it was Williams' fumble at his 1 with just more than 2 minutes left that led to New Orleans' clinching TD.
It was the first time Carolina lost in Louisiana since 2001 and quarterback Jake Delhomme's first loss in the Louisiana Superdome. The Panthers blew a 17-3 lead.