Sony Music says "SOULmate" will hit shelves Dec. 1 with 10 new tracks written before Neale's August 2007 accident.
The first single, "Lonesome Highway," will hit radio and iTunes next Tuesday.
Sony says the song was co-produced and co-written by Neale, and touches on his journey of recovery, supported by his wife, Michaela, daughter Yasmin and numerous others.
Neale was in critical condition in hospital after being hit by a car while driving his Vespa motor scooter in Toronto on Aug. 3, 2007.
Toronto police charged a man under the Highway Traffic Act with making an unsafe turn.
Sony says the new album, the band's fifth, contains 10 tracks written before Neale's accident and recorded over the last six months after his recovery.
"It takes me more time now, but I still orchestrate the room," Neale said in a statement.
All proceeds from the sale of "SOULmate" will go to the Haydain Neale Family Trust.
Jacksoul's previous hits include "Can't Stop" and "Still Believe in Love."