DEERFIELD, Mass. (AP) — Irwin Rose, a biochemist who shared the 2004 Nobel Prize in chemistry for discovering a way that cells destroy unwanted proteins — a key for developing new cancer therapies — has died. He was 88.
Janet Wilson of the University of California, Irvine — where Rose was a researcher — says Rose died in his sleep Tuesday in Deerfield, Massachusetts.
Rose — along with Israelis Aaron Ciechanover and Avram Hershko — discovered how plant and animal cells use a chemical “kiss-of-death” to mark old and damaged proteins so they can be destroyed.
Rose did the Nobel work during his career at the Fox Chase Cancer Center in Philadelphia.
He became a UCI researcher after retiring in 1997.
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