Israeli Scientists Discover Possible Alzheimer’s Breakthrough

A scientist examining cells in a 96-well plate. These plates allow scientists to look at lots of cells at the same time and directly compare cells that have or have not been treated with a drug, at the Cancer Research UK Cambridge Institute on December 9, 2014 in Cambridge, England. …
Dan Kitwood/Getty Images/Cancer Research UK

The Times of Israel reports: Scientists from Tel Aviv University believe they have made a breakthrough that could help treat Alzheimer’s disease, the university said Wednesday.

Researchers lead by Professor Daniel M. Michaelson managed to change the nature of the APOE gene in mice, which has been associated with the debilitating, neuro-degenerative disease.

The gene has a healthy form called APOE3 and a disease-related form APOE4, which is found in 60 percent of sufferers.

“Researchers have developed a novel mechanism and approach with which to convert the “bad” APOE4 to the “good” APOE3,” a statement from the university said.

The results of the study, which was jointly conducted by the university and the commercial company Artery Ltd., based in California, was published last month in the Journal of Alzheimer’s Disease.

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